Tissue Microarray: An Emerging Potential Research Tool
ثبت نشده
چکیده
Submit Manuscript | http://medcraveonline.com of tissue samples [1,2]. Rationalisation of biomarkers using the conventional histopathological procedure is time consuming, laborious and pricey especially, when several markers are to be tested on various specimens. So, TMA is expected to surmount these substantial problems [3]. Tissue microarrays are produced by harvesting cylindrical tissue cores from different paraffin donor blocks and re-embedding them in an array on a single recipient paraffin block such that multiple specimens can be analyzed at the same time thus, conserving resources by analysis of smallcore biopsies of blocks rather than complete sections [1,4].
منابع مشابه
Analysis of Variance for Gene Expression Microarray Data
Spotted cDNA microarrays are emerging as a powerful and cost-effective tool for large-scale analysis of gene expression. Microarrays can be used to measure the relative quantities of specific mRNAs in two or more tissue samples for thousands of genes simultaneously. While the power of this technology has been recognized, many open questions remain about appropriate analysis of microarray data. ...
متن کاملTissue microarrays: applications in genomic research.
The widespread application of tissue microarrays in cancer research and the clinical pathology laboratory demonstrates a versatile and portable technology. The rapid integration of tissue microarrays into biomarker discovery and validation processes reflects the forward thinking of researchers who have pioneered the high-density tissue microarray. The precise arrangement of hundreds of archival...
متن کاملAnalysis of microarray experiments of gene expression profiling.
The study of gene expression profiling of cells and tissue has become a major tool for discovery in medicine. Microarray experiments allow description of genome-wide expression changes in health and disease. The results of such experiments are expected to change the methods employed in the diagnosis and prognosis of disease in obstetrics and gynecology. Moreover, an unbiased and systematic stud...
متن کاملتحلیل تصاویر ریزآرایه به منظور تشخیص نوع سرطان سینه
Background: Microarray technology is a powerful tool to study and analyze the behavior of thousands of genes simultaneously. Images of microarray have an important role in the detection and treatment of diseases. The aim of this study is to provide an automatic method for the extraction and analysis of microarray images to detect cancerous diseases. Methods: The proposed system consists of t...
متن کاملتحلیل تصاویر ریزآرایه به منظور تشخیص نوع سرطان سینه
Background: Microarray technology is a powerful tool to study and analyze the behavior of thousands of genes simultaneously. Images of microarray have an important role in the detection and treatment of diseases. The aim of this study is to provide an automatic method for the extraction and analysis of microarray images to detect cancerous diseases. Methods: The proposed system consists of t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017